IL1RAP Recombinant Rabbit mAb (S-2655-56)
SKU: 95178954787

IL1RAP Recombinant Rabbit mAb (S-2655-56)

$90.00 $100.00
Save 10%
No.2 Bestseller on horizonhouseperu.org >

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 4 - Jul 9

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

IL1RAP Recombinant Rabbit mAb (S-2655-56)Product Specification Host Rabbit Antigen IL1RAP Synonyms Interleukin 1 receptor accessory protein; IL 1 receptor accessory protein; IL 1RAcP; Interleukin 1 receptor 3 (IL 1R 3; IL 1R3); C3orf13; IL1R3 Immunogen Recombinant Protein Location Secreted, Cell membrane Accession Q9NPH3 Clone Number S 2655 56 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu Positive Sample A673 Purification Protein A Concentration 0. 5 mg ml

Product Specification


Host Rabbit
Antigen IL1RAP
Synonyms Interleukin-1 receptor accessory protein; IL-1 receptor accessory protein; IL-1RAcP; Interleukin-1 receptor 3 (IL-1R-3; IL-1R3); C3orf13; IL1R3
Immunogen Recombinant Protein
Location Secreted, Cell membrane
Accession Q9NPH3
Clone Number S-2655-56
Antibody Type Recombinant mAb
Isotype IgG
Application WB, ICC
Reactivity Hu
Positive Sample A673
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu
ICC 1:500 Hu

Background

IL1RAP (interleukin-1 receptor accessory protein) is a transmembrane glycoprotein that serves as the indispensable co-receptor for all members of the IL-1 cytokine family (IL-1α, IL-1β, IL-33, IL-36) by forming a trimeric ligand–primary receptor–IL1RAP complex whose intracellular TIR domains recruit MyD88, triggering sequential activation of IRAK4/IRAK1/2, TRAF6 and downstream MAPK (p38, JNK, ERK) and NF-κB pathways that drive inflammation, cell survival and proliferation; physiologically expressed at low levels in most normal tissues, IL1RAP is markedly up-regulated on the surface of hematologic and solid tumor cells where it additionally interacts with and amplifies oncogenic receptor tyrosine kinases such as FLT3 and c-Kit, and its high expression correlates with poor prognosis, making it a promising selective target for antibody, CAR-T and small-molecule therapies.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 95178954787

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.8 ★★★★★
Based on 860 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
S
Verified Purchase
Sara Beth Blankenship
Alexandria, US
★★★★★ 4
My puppy loves this!!!
UPDATE: my puppy still loves this toy, but I’m not super impressed with the craftsmanship. The fabric around the Velcro started to fray after just a few days and within a week the Velcro was completely detached from the fabric. She’s still able to play with it for now though. I’ll probably end up taking the ball out of the inside and putting it into a different toy and I’ll just sew some Velcro on so I can open and close it. It does stay charged a long time and my puppy enjoys playing with it but the novelty wears off a lot quicker now that she’s had it a couple of weeks. She’s usually into it for about 5 min and then it just vibrates its way into a corner until I turn it off. My 4 month old chorkie (6 pounds) absolutely loves this toy! I was afraid it might scare her at first but no, as soon as we turned it on she was like “LET ME AT IT!!” We’ve only had a it a few days but so far, it’s been a godsend when we are eating dinner or working or other times when we can’t entertain her as much as we would like to. It wears her out too, and after playing with it for about 20 minutes, it’s nap time. So far the battery life has been great. I fully charged it when it arrived and 3 days later it still hasn’t needed to be charged, and she has played with it for about an hour a day, in 15-20 min increments. I like that it has Velcro instead of a zipper, I think it’s a lot safer. The initial “Hello” when you turn it on is kind of loud but other than that, the noises it makes aren’t super loud. It repeats back the things you say, which took me a while to figure out. My puppy hasn’t barked at it but if you have a barker just keep that in mind, it will basically double the barks. It feels like it’s made pretty well, and my dog is kind of an aggressive chewer (she’s a teething puppy so of course she is) but so far it’s held up really well and she hasn’t been able to get the Velcro undone and get to the ball in the middle but if you have a bigger dog they might be able to. The Velcro is pretty strong though. Overall, it’s super cute and it makes my puppy happy which makes me happy! I definitely recommend to anyone who has a puppy or a dog with a lot of energy and needs something to keep them occupied for a while. I will say, after about 30 minutes max, my puppy is kind of over it but that’s a lot longer than anything else has kept her attention so I consider that a win. If I remember, I will update after a month or so to say how it’s holding up as far as charging goes and the overall quality of the toy, but so far I’m super impressed.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 1, 2026
L
Verified Purchase
Lindsey D.
Pawtucket, US
★★★★★ 2
Major flaw
My dog liked this, but the charging port part is at the perfect position for dog teeth to catch on (there's a very large indented part with the on/off switch and that), so after only about two weeks of play, the usb C port is ruined and the toy can no longer be charged. Larger dogs or very small dogs might have fewer issues. My dog is a miniature dachshund and he could pick up the toy by biting at that indented part. (Also that "hello" is incredibly grating and if I forgot to turn off the toy would sound hours later, like in the middle of the night when we're sleeping and then my dog wakes up and freaks out.)
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 18, 2026
S
Verified Purchase
Sandra
Birmingham, US
★★★★★ 5
Foxy
Oh my! My grand pup loves his and so do my pups had to order #3
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 31, 2026
D
Verified Purchase
Darin
Birmingham, US
★★★★★ 5
Really cool cat toy for even the most picky cat!
Color: A1-Red, Color: A1-Red
I love it, wow. Our cat is picky with toys, but even he was intrigued by it. It really kept his attention, which is hard to do. It comes with three modes: fast, slow, and interactive. The only thing is that hair can get all trapped up in it because it's a wheel, so keep your house clean I guess lol. The tail also came off once, so you gotta snuggly get it on up there. Really cool cat toy though, I'm happy I got it lol
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 23, 2026
C
Verified Purchase
Cheryl
Charlottesville, US
★★★★★ 1
Not worth the money
Color: A1-Red
My small Chihuahua loved this toy. It kept him entertained until it would stop working. He only gets about 10 minutes of play and it's no longer charged to use. I even bought a second one thinking the first one might have been just bad luck, but nope, the same problem. It seems most of these interactive toys are only given 2 to 3 stars. I'm disappointed but more importantly, my pup is even more.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 24, 2026

recommand products

Minnesota Block M Hairline Stripe Printed Performance 1/4 Zip
155.00
Iowa State Punching Cy Hairline Stripe Printed Performance 1/4 Zip
155.00
Colorado State Ram Scope Printed Performance Polo
128.00
Coastal Carolina Chanticleer Brendon Performance Hoodie
160.00
Auburn Scope Printed Performance Polo
128.00